Disease associations
Disease associations describe reported relationships between CMR phenotypes and clinical disease contexts. They should help readers understand relevance, not replace diagnosis. Disease badges on feature summaries now link to short primers when a stable primer exists.
- Modality
- All modalities
- Pipeline step
- Interpretation
- Outputs
- Feature-level disease badges and ICD context
- Maturity
- Draft interpretation page
Association model
Disease associations are attached to feature summaries. Each association should include a disease label and, where available, an ICD code group.
| Disease context | Commonly relevant phenotype families |
|---|---|
| Heart failure and cardiomyopathy | Ventricular volumes, ejection fraction, mass, strain, atrial size |
| Hypertension and remodeling | LV mass, wall thickness, concentricity, aortic stiffness |
| Valvular disease | Annular/root structure, flow, regurgitant fraction, atrial and ventricular remodeling |
| Atrial fibrillation | Atrial volume, atrial emptying function, cross-chamber coupling |
| Pulmonary hypertension or right-heart disease | RV volumes, RV function, RA size, pulmonary/aortic flow context |
| Myocardial fibrosis or infiltration | Native T1, corrected T1, ECV where available |
Association is not diagnosis
A disease badge means a phenotype is relevant to that disease area in literature or interpretation. It does not mean the phenotype is diagnostic by itself.
Disease primers
Use Disease primers when the reader starts from a clinical condition rather than a phenotype. The first-pass primers cover heart failure and cardiomyopathy, hypertrophic remodeling, ischemic disease, atrial fibrillation, valve disease, pulmonary hypertension, aortopathy, and infiltrative or inflammatory cardiomyopathy.
Implementation rule
Disease badges should stay close to feature definitions so readers can move from a phenotype to clinical context without searching across the site. A future disease-first index can invert that relationship and let readers start from disease labels or ICD code groups.
Source audit
- Draft interpretation layer checked against current disease-badge usage in promoted phenotype pages and
website/src/components/Feature.tsx. - Disease badges are documented as literature-context navigation, not diagnostic classifiers, phenotype-to-ICD association results, or automated disease labels.
docs/data/reference_sources.ymlexists and remains the active source registry for the cited disease-context papers and method sources.- Textbook context boundary: broad clinical textbook context is not surfaced here because the page-specific phenotype literature and disease-primer routing rules are sufficient for this draft.